چکیده:
Background. Exercise has significant affects on free radical production. Objective. The objective of the present
study was to explore the effect of vitamin C supplementation on lipid peroxidation and lactate levels in sedentary
individuals who performed exhaustion exercised. Methods. 10 healthy sedentary male athletes participated to study.
They were supplemented with 300 mg oral vitamin C (L-ascorbic acid, Ester-C Plus 500 mg, Solgar-USA) and
subjected to acute exhaustion exercise by fatigue developed one time a week for 4 weeks. Exhaustion exercises were
carried out until exhaustion developed according to Bruce protocol once a week for 4 weeks. Blood samples were
collected from the subjects four times, at the beginning and at the end of the supplementation and before and after
exercise, over the 4-weeks study period. The samples were used to analyze MDA, GSH, GSH-Px, CAT, SOD and
NO levels by using ELISA colorimetric method and plasma lactate levels by an autoanalyzer device. Results.
Exhaustion MDA, GSH, GSH-Px, CAT, SOD and NO levels measured both before and after supplementation were
higher than resting levels (p<0.05). MDA, NO and lactate levels that were elevated in exhaustion before
supplementation decreased significantly after vitamin C supplementation (p<0.05). Conclusion. The results of our
study indicate that the increase in free radical production and lactate levels due to by 4-week exhaustion exercise
were offset by vitamin C supplementation. It can be argued in conclusion that supplementation of physiologic doses
of vitamin C may be useful for athlete health and performance.
خلاصه ماشینی:
"Effect of Vitamin C Supplementation on Lipid Peroxidation and Lactate Levels in Individuals Performing Exhaustion Exercise 1Suleyman Patlar*, 2Abdulkerım Kasım Baltaci, 2Rasim Mogulkoc, 3Mehmet Gunay 1Faculty of Sport Sciences, Selcuk University, Konya,Turkey.
The objective of the present study was to explore the effect of vitamin C supplementation on lipid peroxidation and lactate levels in sedentary individuals who performed exhaustion exercised.
They were supplemented with 300 mg oral vitamin C (L-ascorbic acid, Ester-C Plus 500 mg, Solgar-USA) and subjected to acute exhaustion exercise by fatigue developed one time a week for 4 weeks.
The results of our study indicate that the increase in free radical production and lactate levels due to by 4-week exhaustion exercise were offset by vitamin C supplementation.
Vitamin C, Exercise, Free Radicals, Antioxidant Activity, Lactate INTRODUCTION Many researchers concentrate on the relation between nutrition on one hand and development and maintaining performance on the other (1-3).
Vitamin C supplementation was reported to increase systemic and pulmonary antioxidant capacity and prevented oxidative damage and improved pulmonary function during exercise (6).
The present study was aimed to explore the effect of vitamin C supplementation on lipid peroxidation and lactate levels in individuals who were subjected to exhaustion exercise.
Pre- and post-vitamin supplementation exhaustion MDA values were found significantly higher than resting MDA levels in the present study.
CONCLUSION The results of our study indicated that vitamin C supplementation prevented the increase in lactate levels and free radical production caused by 4-weeks exhaustion exercise."